Role Delineation Document (RDD)
..Under update..
Domain 1: Management of Spontaneous and Experimentally Induced Diseases and Conditions |
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Tasks | Knowledge | |
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During B.V.Sc (equivalent to DVM) / M.V.SC / Ph.D Program |
None |
K1. Diagnostic procedure
K2. Surgical techniques associated with diagnostic (e.g. exploratory biopsy), therapeutic purpose (e.g. tumor removal) and creation of animal models. K3. Immunotherapy (e.g. antibody response; cellular immunity; species-specific immune response) K4. Nutrition with emphasis on effects of deficiency or toxicity |
At the time of certification |
T1. Prevent spontaneous or unintended disease or condition T2. Control spontaneous or unintended disease or condition T3. Diagnose disease or condition as appropriate T4. Treat disease or condition as appropriate |
K5. Anatomy with emphasis on features which have significance with regard to clinical medicine (e.g. rat Harderian gland) or experimental medicine (e.g. coronary artery anatomy of the pig, which allows use for induced infarcts; Circle of Willis anatomy in gerbils, which allows use in stroke models). K6. Physiology with emphasis on normative data and characteristics (e.g. seasonal changes in squirrel monkeys; coprophagia in rabbits), metabolic differences (e.g. hypoglycemia in squirrel monkeys) or metabolism of induced disease (e.g. streptozotocin-induced diabetes mellitus; bleomycin and other agents induced fibrosis), reproductive physiology, and clinically significant physiological features. K7. Parasitology with emphasis on parasitic diseases that can become established in a colony and zoonotic parasitic diseases. K8. Microbiology with emphasis on organisms of clinical significance, subclinical infections that cause physiologic, biochemical, and/or immunologic alterations, zoonotic disease organisms, organisms and experimentally to induce infection and unintended infections (e.g. infections associated with chronic vascular cannulation), and sampling and culture techniques for such organisms. K9. Anatomic pathology including pathogenesis of significant naturally occurring (e.g. tuberculosis) and experimentally induced (e.g. collagen induced arthritis) diseases, typical gross and histopathologic lesions (e.g. age-related changes, adverse phenotypes associated with genetically modified rodents) and pertinent anatomic pathology techniques. K10. Pharmacology with emphasis on drugs used to treat disease and drugs used to induce diseases which mimics human diseases (e.g., indications, use and contraindications of drugs; adverse reactions; adverse interactions; mechanisms of action; species specific toxicity), and drugs used to induce disease (e.g., azoxymethane to induce neoplasia, or Dextran sulfate sodium (DSS) to induce colitis K11. Epidemiology including species-specific susceptibility to induced disease (e.g. modes of disease transmission, latency; persistence; prevalence; incidence). K12. Preventive medicine (e.g. immunization; quarantine; prescreening tests) K13. Diagnostic procedures
K14. Genetics with emphasis on control and treatment of naturally occurring and experimentally induced disease, predisposition to disease, and modes of inheritance. |
Domain 2: Management of Pain and Distress |
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Tasks | Knowledge | |
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During B.V.Sc (DVM) / M.V.Sc / Ph.D program |
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K1. Anatomy and physiology of pain and distress K2. Patient monitoring K3. Critical and post-procedural care techniques K4. Methods of euthanasia |
At the time of certification |
T1. Recognize pain and/or distress T2. Minimize or eliminate pain and/or distress T3. Administration of anesthesia and assessment of stages T4. Recommended Euthanasia procedures |
K5. Assessment of pain and distress and measures to alleviate pain and suffering during the course of experimentation K6. Causes of pain K7. Causes of distress K8. Effects of pain and distress on normative physiology and on research studies. K9. Pharmacological interventions for pain and distress and their effects on physiology, including age and species differences for such interventions, and depth and duration of analgesia provided by such interventions. K10. Nonpharmacological interventions for pain and distress and their effects on physiology, including age and species differences for such interventions. K11. Humane endpoint criteria and euthanasia. |
Domain 3: Research |
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Tasks | Knowledge | |
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During B.V.Sc (DVM) / M.V.Sc / Ph.D program |
None |
K1. Principles of experimental design, statistics and research methodology K2. Bio methodology techniques (e.g. collection of blood, body fluids, tissues, handling and restraint, administration of compounds and treatments) K3. Animal models including normative biology relevant to the research (e.g. background lesions of common strains). K4. Characterization of animal models (e.g. phenotyping, behavioral assessment) K5. Genetics and nomenclature |
At the time of certification |
T1. Facilitate or provide research support T2. Advise and consult with investigators on matters related to their research T3. Design and conduct research |
K6. Research methods and equipment (e.g. antibody production; adjuvants; tumor induction; imaging; data collection techniques such as telemetry; observation; behavioral assessment methods) K7. Gnotobiotics K8. Experimental surgical techniques and instrumentation K9. Information resources K10. Scientific writing K11. 3R’s techniques (Replacement, Reduction and Refinement) K12. Effective methods for communicating research-related concerns K13. Aseptic requirements for performing surgery K14. Genetic modification / engineering technology including application of molecular biology techniques (e.g. Humanized mice). K15. Genomics, metabolomics, and proteomics |
After certification |
T1. Collaborate with other scientists on research projects |
K16. Grant application, review and funding mechanisms |
Domain 4: Animal care |
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Tasks | Knowledge | |
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During a B.V.Sc (DVM) / M.V.Sc / Ph.D program |
None |
K1. Species-specific husbandry (e.g. nutrition, housing, exercise) K2. Methods of sterilization, sanitation, and decontamination K3. Animal identification systems K4. Pest control (e.g. methods, hazards, and toxicity) K5. Environmental monitoring K6. Watering and feeding (e.g. liquid or restricted diets, ad libitum) |
At the time of certification |
T1. Develop animal husbandry programs with problem solving practices T2. Manage or provide indirect management / oversight of animal husbandry programs T3. Manage or provide indirect management / oversight of laboratory animal facilities |
K7. Breeding colony management (e.g. systems and records, genetic monitoring). K8. Environmental causes of physiological alterations in animals and their effects on research (e.g. sound, light, temperature, humidity, housing systems). K9. Environmental enrichment, species-specific behavioral and psychological needs including creation and maintenance of appropriate social pairs or groups. K10. Quality assurance techniques for animal care-related equipment (e.g. effectiveness of cage sanitation verification) and supplies (e.g. water, feed and bedding). K11. Animal procurement considerations (e.g. vendor surveillance, genetic monitoring, transportation). K12. Pathogen-free barriers (exclusion), maintenance of pathogen-free colonies via sentinel use and health surveillance programs K13. Containment facilities |
After certification |
T4. Design laboratory animal facilities |
K14. Selection-criteria for animal care-related equipment and supplies. K15. Fiscal management as it relates to budgetary and financial issues associated with animal facility management (e.g. per diem rate setting; equipment cost comparisons). K16. Human resource management as it relates to operation of animal care and use programs. K17. Disaster planning K18. Facility planning, design, and construction K19. Mechanical, electrical and plumbing systems K20. Waste management K21. Housing systems (e.g. high density caging, aquatics) |
Domain 5: Regulatory Responsibilities |
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Tasks | Knowledge | |
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During a B.V.Sc / M.V.Sc / Ph.D program |
None |
K1. Laws, regulations, policies and standards K2. Animal welfare organizations, Animal Welfare Board of India - their role, functions and current status. Laws on animal welfare. K3. Prevention of Cruelty to Animals (PCA) Act, 1960 {59 of 1960). Role and function of CPCSEA. K4. Role of veterinarians in animal welfare, code of conduct and ethics. |
At the time of certification |
T1. Perform direct or delegated Attending Veterinarian responsibilities. T2. Advocate for humane care and use of animals. T3. Provide advice to occupational health and safety program T4. Provide advise on biological, chemical and radiation hazards in an animal research program T5. Serve as a member of IAEC (IACUC) T6. Review protocols and provide advise to investigators and the IAEC (IACUC). |
K5. Rules and regulations of CPCSEA. K6. Role and function of the IAEC (IACUC) K7. Protocols review including harm benefit analysis K8. Role and function of the Institutional Biosafety Committee (IBC). K9. Role and function of AAALAC international K10. Good Laboratory Practices (GLP) K11. International laws, regulations, policies and standards. K12. Guide for the Care and Use of Laboratory Animals (NRC). K13. AVMA Guidelines for the Euthanasia of Animals (AVMA) K14. Biosafety in Microbiological and Biomedical Laboratories (BMBL) K15. Live Animals Regulations (IATA - International Air Transportation Association) K16. Occupational Health and Safety in the Care and Use of Research Animals (ILAR / NRC). K17. Responsible conduct of research K18. Occupational Health and Safety in the Care and Use of Research Animals (ILAR / NRC). K19. Facility inspection and program review. |
After certification |
None |
K19. International laws, policies, and standards of other countries or regions (e.g. USDA regulations; EU Directives; CCAC etc.) |
Domain 6: Education |
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Tasks | Knowledge | |
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During a B.V.Sc (DVM) / M.V.Sc / Ph.D program |
None |
K1. Philosophy and ethics of animal used, history and value of animal research |
At the time of certification |
T1. Train personnel in animal care and use T2. Maintain current knowledge and continued competence in laboratory animal medicine |
K2. Educational resources K3. Certification programs K4. Societal issues involving use of animals.
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After certification |
T3. Provide education in academic and/or laboratory animal residency programs T4. Outside of formal training programs, mentor those interested in or involving in laboratory animal medicine. T5. Provide community outreach on animal care and use. |
None |
abbreviations
LASA India: Laboratory Animal Scientists Association, India; |